Bovine explant model of degeneration of the intervertebral disc
نویسندگان
چکیده
منابع مشابه
Bovine explant model of degeneration of the intervertebral disc
BACKGROUND Many new treatments for degeneration of the intervertebral disc are being developed which can be delivered through a needle. These require testing in model systems before being used in human patients. Unfortunately, because of differences in anatomy, there are no ideal animal models of disc degeneration. Bovine explant model systems have many advantages but it is not possible to inje...
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Introduction: Intervertebral Disc Disease (IVDD) afflicts nearly 12 million people in the United States and is a leading cause of lumbar spine-related lowerback pain [1]. Conventional magnetic resonance imaging (MRI) has a critical role in detection of late-stage degenerative changes (such as changes in disc morphology, height, bulge and herniation). Recently, other MRI methods have been propos...
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چکیده ندارد.
15 صفحه اولDegeneration of the intervertebral disc
The intervertebral disc is a cartilaginous structure that resembles articular cartilage in its biochemistry, but morphologically it is clearly different. It shows degenerative and ageing changes earlier than does any other connective tissue in the body. It is believed to be important clinically because there is an association of disc degeneration with back pain. Current treatments are predomina...
متن کاملIntervertebral Disc Dynamics and Degeneration
Degenerative disc disease is a serious health problem worldwide, whose etiological basis – mechanical stimulus, biochemical changes, or natural aging – is poorly understood. While the disc’s known function is that of dynamic shock absorber, its dynamic response has not been fully characterized throughout the disc health spectrum (from healthy to degenerate). Therefore, this study aimed to corre...
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ژورنال
عنوان ژورنال: BMC Musculoskeletal Disorders
سال: 2008
ISSN: 1471-2474
DOI: 10.1186/1471-2474-9-24